{"id":23373,"date":"2025-04-13T17:39:38","date_gmt":"2025-04-13T17:39:38","guid":{"rendered":"https:\/\/onderzoekschemicals.com\/?post_type=product&p=23373"},"modified":"2025-06-30T11:36:38","modified_gmt":"2025-06-30T11:36:38","slug":"escaline-fumarate","status":"publish","type":"product","link":"https:\/\/onderzoekschemicals.com\/sk\/shop\/bijna-verboden\/escaline-fumarate\/","title":{"rendered":"Eskal\u00edn fumar\u00e1t"},"content":{"rendered":"

Eskal\u00edn fumar\u00e1t \u2013 inovat\u00edvny psychedelick\u00fd fenetylam\u00edn pre vedeck\u00fd v\u00fdskum<\/strong><\/h1>\n

N\u00e1zov produktu:<\/strong> Eskal\u00edn fumar\u00e1t
\nCel\u00e9 meno:<\/strong> 3,5-dimetoxy-4-etoxyfenetylam\u00edn fumar\u00e1t
\nChemick\u00e1 trieda:<\/strong> Psychedelick\u00fd fenetylam\u00edn
\nMolekul\u00e1rny vzorec (fumar\u00e1tov\u00e1 so\u013e):<\/strong> C12H19NO3 C4H4O4
\nMolekulov\u00e1 hmotnos\u0165:<\/strong> \u00b1 325,34 g\/mol
\nVzh\u013ead:<\/strong> Biely a\u017e svetlo\u017elt\u00fd pr\u00e1\u0161ok (kry\u0161talick\u00fd)
\n\u010distota:<\/strong> \u2265 98% (testovan\u00e9 pomocou HPLC a NMR)
\nSynonym\u00e1:<\/strong> Eskal\u00edn hemi-fumar\u00e1t, 4-etoxy-meskal\u00edn<\/p>\n

\n

\ud83e\uddec \u010co je escal\u00edn fumar\u00e1t?<\/strong><\/h2>\n

Escaline je psychedelick\u00fd fenetylam\u00edn<\/strong> a \u0161truktur\u00e1lny anal\u00f3g meskal\u00ednu s etoxyskupina<\/strong> namiesto metoxyskupiny v polohe 4. Fumar\u00e1tov\u00e1 verzia (vo forme soli) pon\u00faka vylep\u0161en\u00fa stabilita a rozpustnos\u0165<\/strong>, ide\u00e1lne pre presn\u00fa laborat\u00f3rnu anal\u00fdzu.<\/p>\n

\u26a0\ufe0f Len na analytick\u00fd a farmakologick\u00fd v\u00fdskum. Nie je ur\u010den\u00e9 na \u013eudsk\u00fa spotrebu.<\/em><\/p><\/blockquote>\n

\n

\ud83d\udd2c Aplik\u00e1cie vo v\u00fdskume<\/strong><\/h2>\n

Escaline je vy\u0161etrovan\u00fd kv\u00f4li jeho agonistick\u00fd \u00fa\u010dinok na serotonergn\u00e9 receptory<\/strong> (najm\u00e4 5-HT2A) a jeho \u0161truktur\u00e1lnu podobnos\u0165 s klasick\u00fdmi psychedelikami.<\/p>\n

Mo\u017en\u00e9 aplik\u00e1cie:<\/h3>\n
    \n
  • \u0160t\u00fadie v\u00e4zby na receptory<\/strong> v serotonergn\u00fdch dr\u00e1hach<\/li>\n
  • Neurochemick\u00e1 porovn\u00e1vacia \u0161t\u00fadia<\/strong> s meskal\u00ednom, proskal\u00ednom a izoproskal\u00ednom<\/li>\n
  • Farmakokinetick\u00e9 simul\u00e1cie<\/strong> a anal\u00fdzy SAR (vz\u0165ah medzi \u0161trukt\u00farou a aktivitou)<\/li>\n
  • Modelovanie vedomia in vitro<\/strong> prostredn\u00edctvom bunkov\u00fdch l\u00edni\u00ed a met\u00f3d anal\u00fdzy receptorov<\/li>\n<\/ul>\n
    \n

    \ud83e\uddea Pou\u017eitie a laborat\u00f3rne pokyny<\/strong><\/h2>\n
      \n
    • Rozpustnos\u0165:<\/strong> \u013dahko rozpustn\u00fd v etanole, DMSO; mierne rozpustn\u00fd vo vode<\/li>\n
    • Odpor\u00fa\u010dan\u00e1 koncentr\u00e1cia (in vitro):<\/strong> 5\u201330 \u00b5M v z\u00e1vislosti od typu testu<\/li>\n
    • Ulo\u017ei\u0165:<\/strong> Such\u00e9, vzduchotesn\u00e9 a pri teplote 2\u20138 \u00b0C<\/li>\n
    • Formul\u00e1r:<\/strong> Hemi-fumar\u00e1t (pomer eskal\u00ednu a fumar\u00e1tu 1:0,5)<\/li>\n
    • Odpor\u00fa\u010dan\u00e9 OOP:<\/strong> Rukavice, ochrann\u00e9 okuliare, pr\u00e1ca v prievane s ods\u00e1van\u00edm<\/li>\n<\/ul>\n
      \n

      \u274c Nev\u00fdhody a rizik\u00e1<\/strong><\/h2>\n

      Hoci je Escaline cenn\u00fd pre vedeck\u00fd v\u00fdskum, existuj\u00fa ur\u010dit\u00e9 obmedzenia:<\/p>\n

        \n
      • Obmedzen\u00fd v\u00fdskum:<\/strong> K dispoz\u00edcii je ve\u013emi m\u00e1lo recenzovan\u00fdch \u00fadajov<\/li>\n
      • Psychoakt\u00edvny profil:<\/strong> Mo\u017en\u00fd siln\u00fd \u00fa\u010dinok v pr\u00edpade n\u00e1hodnej expoz\u00edcie<\/li>\n
      • Legislat\u00edva:<\/strong> Mo\u017eno nez\u00e1konn\u00e9 pod\u013ea analogickej legislat\u00edvy (NL\/BE\/E\u00da)<\/li>\n
      • Citlivos\u0165 \u0161trukt\u00fary:<\/strong> Mal\u00e9 molekul\u00e1rne zmeny m\u00f4\u017eu dramaticky zmeni\u0165 biologick\u00e9 reakcie<\/li>\n<\/ul>\n
        \n

        \ud83d\udcca Anal\u00fdza vzorky v laborat\u00f3riu<\/strong><\/h2>\n

        K\u00f3d d\u00e1vky:<\/strong> ESC-FUM-2025-07
        \nTestovan\u00e9 pou\u017e\u00edvate\u013eom:<\/strong> DeltaChem Scientifics BV
        \nAnal\u00fdza d\u00e1tumu:<\/strong> 2025-06-10<\/p>\n\n\n\n\n\n\n\n\n\n
        Met\u00f3da anal\u00fdzy<\/th>\nV\u00fdsledok<\/th>\n<\/tr>\n<\/thead>\n
        HPLC<\/td>\n\u010cistota 98,61 TP3T<\/td>\n<\/tr>\n
        NMR spektroskopia<\/td>\nToto\u017enos\u0165 potvrden\u00e1<\/td>\n<\/tr>\n
        FTIR<\/td>\nFunk\u010dn\u00e9 skupiny pod\u013ea<\/td>\n<\/tr>\n
        GC-MS<\/td>\n\u017diadne ne\u010distoty neboli zisten\u00e9<\/td>\n<\/tr>\n
        \u0164a\u017ek\u00e9 kovy<\/td>\nNedetekovate\u013en\u00e9 (<0,01%)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
        \n

        \u2753 \u010casto kladen\u00e9 ot\u00e1zky (FAQ)<\/strong><\/h2>\n

        \u010co presne rob\u00ed Escaline?<\/h3>\n

        Escaline je pravdepodobne 5-HT2A agonista<\/strong>, podobne ako meskal\u00edn, \u010do vedie k zmen\u00e1m vo vn\u00edman\u00ed a vedom\u00ed. Presn\u00e1 farmakodynamika v\u0161ak st\u00e1le nie je \u00faplne presk\u00faman\u00e1.<\/p>\n

        Je Escaline v Holandsku leg\u00e1lny?<\/h3>\n

        Mo\u017eno nie.<\/strong> Hoci sa to \u010dasto v\u00fdslovne neuv\u00e1dza, m\u00f4\u017ee to by\u0165 analogick\u00e1 legislat\u00edva<\/strong> p\u00e1d. Odpor\u00fa\u010da sa pr\u00e1vna konzult\u00e1cia.<\/p>\n

        Je Escaline to ist\u00e9 ako meskal\u00edn?<\/h3>\n

        Nie.<\/strong> Je to anal\u00f3g: Escaline obsahuje etoxyskupina<\/strong> namiesto 4-metoxy skupiny meskal\u00ednu, ktor\u00e1 ovplyv\u0148uje \u00fa\u010dinnos\u0165 a v\u00e4zbov\u00fd profil.<\/p>\n

        M\u00f4\u017eem si Escaline vysk\u00fa\u0161a\u0165 alebo vysk\u00fa\u0161a\u0165 s\u00e1m?<\/h3>\n

        Nie.<\/strong> Tento produkt je ur\u010den\u00fd len na pou\u017eitie profesion\u00e1lne laborat\u00f3rne pou\u017eitie<\/strong> a je nie je schv\u00e1len\u00e9 na \u013eudsk\u00fa spotrebu<\/strong>.<\/p>\n

        Pre\u010do sa dod\u00e1va ako fumar\u00e1t?<\/h3>\n

        The fumar\u00e1tov\u00e1 forma<\/strong> ponuky:<\/p>\n

          \n
        • Lep\u0161ie chemick\u00e1 stabilita<\/strong><\/li>\n
        • Menej hygroskopick\u00e9 spr\u00e1vanie<\/strong><\/li>\n
        • Jednoduch\u0161ie d\u00e1vkovanie<\/strong> vo v\u00fdskumnom prostred\u00ed<\/li>\n<\/ul>\n
          \n

          \u26a0\ufe0f Pr\u00e1vne a bezpe\u010dnostn\u00e9 vyhl\u00e1senie<\/strong><\/h2>\n

          Nie na konzum\u00e1ciu.<\/strong> Dostupn\u00e9 len pre akademick\u00e9 in\u0161tit\u00facie, v\u00fdskumn\u00e9 zariadenia a akreditovan\u00e9 laborat\u00f3ri\u00e1. Predaj malolet\u00fdm osob\u00e1m je zak\u00e1zan\u00fd. V\u00fdrobca ani predajca nepreberaj\u00fa \u017eiadnu zodpovednos\u0165 za zneu\u017eitie.<\/p>","protected":false},"excerpt":{"rendered":"

          Vlastnosti eskal\u00edn fumar\u00e1tu<\/h3>\n

          Synonymum:<\/strong> 3,5-dimetoxy-4-etoxyfenetylam\u00edn fumar\u00e1t
          \n\u010c\u00edslo CAS:<\/strong> 39201-82-6
          \nVzorec:<\/strong> 2-{3,5-dimetoxy-4-etyloxyfenyl}et\u00e1n-1-am\u00edn fumar\u00e1t
          \nMol\u00e1rna hmotnos\u0165:<\/strong> 341,4 g\/mol
          \n\u010distota:<\/strong> >97%<\/p>","protected":false},"featured_media":20226,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[322,535,80],"product_tag":[326],"class_list":{"0":"post-23373","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-bijna-verboden","7":"product_cat-escaline","8":"product_cat-fenethylamine","9":"product_tag-nl","11":"first","12":"instock","13":"taxable","14":"shipping-taxable","15":"purchasable","16":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/onderzoekschemicals.com\/sk\/wp-json\/wp\/v2\/product\/23373","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onderzoekschemicals.com\/sk\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/onderzoekschemicals.com\/sk\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/onderzoekschemicals.com\/sk\/wp-json\/wp\/v2\/comments?post=23373"}],"version-history":[{"count":3,"href":"https:\/\/onderzoekschemicals.com\/sk\/wp-json\/wp\/v2\/product\/23373\/revisions"}],"predecessor-version":[{"id":26544,"href":"https:\/\/onderzoekschemicals.com\/sk\/wp-json\/wp\/v2\/product\/23373\/revisions\/26544"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/onderzoekschemicals.com\/sk\/wp-json\/wp\/v2\/media\/20226"}],"wp:attachment":[{"href":"https:\/\/onderzoekschemicals.com\/sk\/wp-json\/wp\/v2\/media?parent=23373"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/onderzoekschemicals.com\/sk\/wp-json\/wp\/v2\/product_brand?post=23373"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/onderzoekschemicals.com\/sk\/wp-json\/wp\/v2\/product_cat?post=23373"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/onderzoekschemicals.com\/sk\/wp-json\/wp\/v2\/product_tag?post=23373"}],"curies":[{"name":"pracovn\u00fd list","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}