DMXE 40 мг гранулы (дезоксиметоксетамин)

DMXE (Deoxymethoxetamine) 40mg Pellets – Scientific Product Documentation

🔬Химические характеристики

DMXE (2′-Oxo-PCE-d10) is a research chemical belonging to the arylcyclohexylamine class, structurally related to MXE (methoxetamine) and ketamine. These pellets are formulated for precise scientific research.

Основные параметры:

• Название ИЮПАК : 2-(3,4-Диметилфенил)-2-(этиламино)циклогексанон

• Молекулярная формула : C₁₆H₂₃NO

• Молекулярный вес : 245.36 g/mol

• Чистота : ≥98% (GC-MS analysis)

• Shape : Round, 4mm diameter pellets

• Color : Light beige to white

• Растворимость : 15 mg/ml in water (at 25°C)

🧪Научные приложения

1. Нейрофармакологические исследования :

   • NMDA receptor antagonism studies

   • Sigma-1 receptor interaction assays

2. Поведенческая нейронаука :

   • Effects on learning behavior in laboratory animals

   • Dose-dependent dissociative effects

3. Психофармакология :

   • Comparative studies with related dissociatives

   • Research into neuroplastic effects

⚖️Recommended Research Protocols

Экспериментальные указания:

*Note: Non-linear pharmacokinetics above 25 mg/kg*

⚠️Safety Profile & Risk Management

1. Токсикологические данные :

   • LD₅₀ (крыса, перорально): 320 мг/кг

   • NOAEL: 5 mg/kg/day (7-day study)

2. Спектр побочных эффектов :

   • <10 mg: Subtle behavioral effects

   • 10-30 mg: Motor incoordination

   • 30 mg: Potential respiratory depression

3. Критические взаимодействия :

   • Опасный : Opioids, GABA-ergics

   • Рискованно : Stimulants, MAO inhibitors

📊Контроль качества и аналитические данные

• Чистота ВЭЖХ : 98.5% (C18 column, 70:30 H₂O:MeCN)

• Uniformity : ±5% weight deviation (n=20 pellets)

• Disintegration time : <15 minutes (in simultaneous gastric juice)

• Данные о стабильности :

  • Shelf life: 24 months at 15-25°C

  • Moisture sensitivity: <0.5% weight gain (93% RH)

❓Часто задаваемые исследовательские вопросы

В1: Каков механизм действия?
A: Primary NMDA receptor antagonism with secondary dopamine reuptake inhibition.

Q2: How does the potency compare to ketamine?
A: ~0.6x the potency of ketamine but a longer half-life (4-6 hours).

Q3: Are there any neurotoxic risks?
A: Olney’s lesions were not observed at <50 mg/kg (rat study).

Q4: What is the optimal storage method?
A: In the original packaging at 15-25°C, protected from moisture.

📌Ограничения исследования

• Limited data on chronic administration

• Unknown effects on glutamate transmission

• Variable biotransformation between species

🔍Conclusion for Researchers

DMXE 40mg pellets offer a standardized formulation for precise dissociative research, with consistent dose delivery and good stability. The pellet form facilitates quantitative administration in animal studies.

Scientific disclaimer: This product is intended solely for in vitro research and authorized preclinical studies. Not for human use. All experiments must comply with applicable ethical guidelines and local regulations. Please be aware of the special status of psychoactive research substances in your jurisdiction.