{"id":23358,"date":"2025-04-13T17:39:37","date_gmt":"2025-04-13T17:39:37","guid":{"rendered":"https:\/\/onderzoekschemicals.com\/?post_type=product&p=23358"},"modified":"2025-11-28T11:30:33","modified_gmt":"2025-11-28T11:30:33","slug":"dmxe-40mg-pellets-deoxymethoxetamine","status":"publish","type":"product","link":"https:\/\/onderzoekschemicals.com\/pt\/shop\/arylcyclohexylamine\/dmxe-40mg-pellets-deoxymethoxetamine\/","title":{"rendered":"Pellets DMXE 40mg (Desoximetoxetamina)"},"content":{"rendered":"

Pellets de DMXE (Deoximetoxetamina) 40mg \u2013 Documenta\u00e7\u00e3o Cient\u00edfica do Produto<\/span><\/span><\/strong><\/h3>\n

\ud83d\udd2cEspecifica\u00e7\u00f5es Qu\u00edmicas<\/span><\/span><\/strong><\/h4>\n

O DMXE (2\u2032-Oxo-PCE-d10) \u00e9 um composto qu\u00edmico de pesquisa pertencente \u00e0 classe das arilciclohexilaminas, estruturalmente relacionado ao MXE (metoxetamina) e \u00e0 cetamina. Estes gr\u00e2nulos s\u00e3o formulados para pesquisa cient\u00edfica de precis\u00e3o.<\/span><\/span><\/p>\n

Par\u00e2metros principais:<\/span><\/span><\/em><\/p>\n

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    Nome IUPAC<\/span><\/span><\/strong> : 2-(3,4-Dimetilfenil)-2-(etilamino)ciclohexanona<\/span><\/span><\/p>\n<\/li>\n

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    F\u00f3rmula molecular<\/span><\/span><\/strong> : C\u2081\u2086H\u2082\u2083NO<\/span><\/span><\/p>\n<\/li>\n

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    Peso molecular<\/span><\/span><\/strong> : 245,36 g\/mol<\/span><\/span><\/p>\n<\/li>\n

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    Pureza<\/span><\/span><\/strong> : \u226598% (an\u00e1lise GC-MS)<\/span><\/span><\/p>\n<\/li>\n

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    Forma<\/span><\/span><\/strong> Pelotas redondas com 4 mm de di\u00e2metro.<\/span><\/span><\/p>\n<\/li>\n

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    Cor<\/span><\/span><\/strong> Bege claro a branco<\/span><\/span><\/p>\n<\/li>\n

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    Solubilidade<\/span><\/span><\/strong> : 15 mg\/ml em \u00e1gua (a 25\u00b0C)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

    \ud83e\uddeaAplica\u00e7\u00f5es Cient\u00edficas<\/span><\/span><\/strong><\/h4>\n
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      Pesquisa neurofarmacol\u00f3gica<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

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        Estudos de antagonismo do receptor NMDA<\/span><\/span><\/p>\n<\/li>\n

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        Ensaios de intera\u00e7\u00e3o do receptor sigma-1<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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        Neuroci\u00eancia Comportamental<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

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          Efeitos no comportamento de aprendizagem em animais de laborat\u00f3rio<\/span><\/span><\/p>\n<\/li>\n

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          Efeitos dissociativos dependentes da dose<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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          Psicofarmacologia<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

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            Estudos comparativos com dissociativos relacionados<\/span><\/span><\/p>\n<\/li>\n

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            Pesquisas sobre efeitos neuropl\u00e1sticos<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

            \u2696\ufe0fProtocolos de pesquisa recomendados<\/span><\/span><\/strong><\/h4>\n

            Diretrizes experimentais:<\/span><\/span><\/em><\/p>\n

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            Modelo<\/span><\/span><\/th>\nDosagem<\/span><\/span><\/th>\nFreq\u00fc\u00eancia<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
            Em vitro<\/span><\/span><\/td>\n10-50 \u03bcM<\/span><\/span><\/td>\nExposi\u00e7\u00e3o \u00fanica<\/span><\/span><\/td>\n<\/tr>\n
            Pequenos roedores<\/span><\/span><\/td>\n5-20 mg\/kg<\/span><\/span><\/td>\n1 vez por dia (m\u00e1ximo de 3 dias)<\/span><\/span><\/td>\n<\/tr>\n
            Primatas<\/span><\/span><\/td>\n1-5 mg\/kg<\/span><\/span><\/td>\ndose \u00fanica<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

            *Nota: Farmacocin\u00e9tica n\u00e3o linear acima de 25 mg\/kg*<\/span><\/span><\/p>\n

            \u26a0\ufe0fPerfil de seguran\u00e7a e gest\u00e3o de riscos<\/span><\/span><\/strong><\/h4>\n
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              Dados toxicol\u00f3gicos<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

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                DL\u2085\u2080 (rato, via oral): 320 mg\/kg<\/span><\/span><\/p>\n<\/li>\n

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                NOAEL: 5 mg\/kg\/dia (estudo de 7 dias)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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                Espectro de efeitos colaterais<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

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                  <10 mg: Efeitos comportamentais sutis<\/span><\/span><\/p>\n<\/li>\n

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                  10-30 mg: Incoordena\u00e7\u00e3o motora<\/span><\/span><\/p>\n<\/li>\n

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                  30 mg: Potencial depress\u00e3o respirat\u00f3ria<\/span><\/span><\/p>\n<\/blockquote>\n<\/li>\n<\/ul>\n<\/li>\n

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                  Intera\u00e7\u00f5es Cr\u00edticas<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

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                    Perigoso<\/span><\/span><\/strong> Opioides, GABA\u00e9rgicos<\/span><\/span><\/p>\n<\/li>\n

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                    Arriscado<\/span><\/span><\/strong> Estimulantes, inibidores da MAO<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

                    \ud83d\udccaControle de Qualidade e Dados Anal\u00edticos<\/span><\/span><\/strong><\/h4>\n
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                      Pureza HPLC<\/span><\/span><\/strong> : 98,5% (coluna C18, 70:30 H\u2082O:MeCN)<\/span><\/span><\/p>\n<\/li>\n

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                      Uniformidade<\/span><\/span><\/strong> : Desvio de peso \u00b15% (n=20 pellets)<\/span><\/span><\/p>\n<\/li>\n

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                      Tempo de desintegra\u00e7\u00e3o<\/span><\/span><\/strong> : <15 minutos (em suco g\u00e1strico simult\u00e2neo)<\/span><\/span><\/p>\n<\/li>\n

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                      Dados de estabilidade<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

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                        Validade: 24 meses a 15-25\u00b0C<\/span><\/span><\/p>\n<\/li>\n

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                        Sensibilidade \u00e0 umidade: ganho de peso <0,5% (93% UR)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

                        \u2753Perguntas frequentes sobre pesquisa<\/span><\/span><\/strong><\/h4>\n

                        Q1: Qual \u00e9 o mecanismo de a\u00e7\u00e3o?<\/span><\/span><\/strong>
                        \n A: Antagonismo prim\u00e1rio do receptor NMDA com inibi\u00e7\u00e3o secund\u00e1ria da recapta\u00e7\u00e3o de dopamina.<\/span><\/span><\/p>\n

                        P2: Qual a pot\u00eancia em compara\u00e7\u00e3o com a cetamina?<\/span><\/span><\/strong>
                        \n A: Pot\u00eancia aproximadamente 0,6 vezes maior que a da cetamina, mas com meia-vida mais longa (4 a 6 horas).<\/span><\/span><\/p>\n

                        P3: Existem riscos neurot\u00f3xicos?<\/span><\/span><\/strong>
                        \n A: As les\u00f5es de Olney n\u00e3o foram observadas em doses <50 mg\/kg (estudo em ratos).<\/span><\/span><\/p>\n

                        Q4: Qual \u00e9 o m\u00e9todo de armazenamento ideal?<\/span><\/span><\/strong>
                        \n A: Na embalagem original, a uma temperatura entre 15 e 25 \u00b0C, protegido da umidade.<\/span><\/span><\/p>\n

                        \ud83d\udcccLimita\u00e7\u00f5es da pesquisa<\/span><\/span><\/strong><\/h4>\n
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                          Dados limitados sobre administra\u00e7\u00e3o cr\u00f4nica<\/span><\/span><\/p>\n<\/li>\n

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                          Efeitos desconhecidos na transmiss\u00e3o de glutamato<\/span><\/span><\/p>\n<\/li>\n

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                          Biotransforma\u00e7\u00e3o vari\u00e1vel entre esp\u00e9cies<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                          \ud83d\udd0dConclus\u00e3o para pesquisadores<\/span><\/span><\/strong><\/h4>\n

                          Os pellets de DMXE 40mg oferecem uma formula\u00e7\u00e3o padronizada para pesquisa dissociativa precisa, com administra\u00e7\u00e3o consistente da dose e boa estabilidade. O formato em pellet facilita a administra\u00e7\u00e3o quantitativa em estudos com animais.<\/span><\/span><\/p>\n

                          Aviso cient\u00edfico: Este produto destina-se exclusivamente \u00e0 pesquisa in vitro e a estudos pr\u00e9-cl\u00ednicos autorizados. N\u00e3o se destina ao uso humano. Todos os experimentos devem estar em conformidade com as diretrizes \u00e9ticas aplic\u00e1veis e as regulamenta\u00e7\u00f5es locais. Esteja ciente do status especial das subst\u00e2ncias psicoativas para pesquisa em sua jurisdi\u00e7\u00e3o.<\/span><\/span><\/em><\/p>","protected":false},"excerpt":{"rendered":"

                          Recursos DMXE<\/span><\/span><\/span><\/span><\/h3>\n

                          Sin\u00f4nimo:<\/span><\/span><\/span><\/span><\/strong> Cloridrato de desoximetoxetamina <\/span><\/span><\/span><\/span>
                          \nN\u00famero CAS:<\/span><\/span><\/span><\/span><\/strong> 681440-83-5 <\/span><\/span><\/span><\/span>
                          \nF\u00f3rmula:<\/span><\/span><\/span><\/span><\/strong> 5-desidro-1,3-quinodimetano <\/span><\/span><\/span><\/span>
                          \nMassa molar:<\/span><\/span><\/span><\/span><\/strong> 103,14 g\/mol <\/span><\/span><\/span><\/span>
                          \nPureza:<\/span><\/span><\/span><\/span><\/strong> >97%<\/span><\/span><\/span><\/span><\/p>","protected":false},"featured_media":29320,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[71,406,429,324],"product_tag":[1234,326],"class_list":{"0":"post-23358","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-arylcyclohexylamine","7":"product_cat-dmxe","8":"product_cat-dmxe-pellets","9":"product_cat-pellets-for-pellet","10":"product_tag-dmxe-40mg-pellets","11":"product_tag-nl","13":"first","14":"instock","15":"taxable","16":"shipping-taxable","17":"purchasable","18":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/onderzoekschemicals.com\/pt\/wp-json\/wp\/v2\/product\/23358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onderzoekschemicals.com\/pt\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/onderzoekschemicals.com\/pt\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/onderzoekschemicals.com\/pt\/wp-json\/wp\/v2\/comments?post=23358"}],"version-history":[{"count":5,"href":"https:\/\/onderzoekschemicals.com\/pt\/wp-json\/wp\/v2\/product\/23358\/revisions"}],"predecessor-version":[{"id":28745,"href":"https:\/\/onderzoekschemicals.com\/pt\/wp-json\/wp\/v2\/product\/23358\/revisions\/28745"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/onderzoekschemicals.com\/pt\/wp-json\/wp\/v2\/media\/29320"}],"wp:attachment":[{"href":"https:\/\/onderzoekschemicals.com\/pt\/wp-json\/wp\/v2\/media?parent=23358"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/onderzoekschemicals.com\/pt\/wp-json\/wp\/v2\/product_brand?post=23358"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/onderzoekschemicals.com\/pt\/wp-json\/wp\/v2\/product_cat?post=23358"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/onderzoekschemicals.com\/pt\/wp-json\/wp\/v2\/product_tag?post=23358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}